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Other sources of ROS include xanthine oxidase, uncoupled NO synthase, and others [61]
Copper imbalance not only heightens oxidative stress but may also interfere with lipid metabolism and signaling, further advancing the neurodegenerative processes in ALS (111)
Together they are studied in preclinical models for somatotropic-axis signaling, pituitary GH pulse amplification, and IGF-1 pathway research
A total of 98 G6PD-associated genes were identified, and out of the 47 implicated signaling pathways, seven were highly likely to be regulated by G6PD-associated genes
