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Human Data: While animal studies (mostly in rats) are overwhelmingly positive, large-scale, peer-reviewed human clinical trials are still limited
Efficacy of the combination of MEK and CDK4/6 inhibitors in vitro and in vivo in KRAS mutant colorectal cancer models
[DOI] [PMC free article] [PubMed] [Google Scholar] 87.Bao J., Lei D., Du Y., Ohlemiller K.K., Beaudet A.L., Role L.W
M., Marcheva B., and Bass J., Circadian Rhythms, Sleep, and Metabolism, Journal of Clinical Investigation 121, no
