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A larger study of 40 patients with relapsed CML treated with one of three different doses of CD4+ (i.e
coli , being more efficient when positioned at the N-terminal rather than at the C-terminal end (Malhotra, 2009)
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Conversely, some evidence indicated that an initial increase in respiration and presumably mitochondrial function driven by BCR crosslinking needed a costimulatory signal from CD40 or TLR9 to be maintained on the first day [76]
