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We also thank Anita-Karina Jaehnke, Regina Sommer-Klu and Christin Wiemuth for their continuous organizational support

Serial vaccination Rather than trying to present multiple antigens together in the form of a mosaic vaccine to the immune system, an alternative approach could be to sequentially vaccinate with different antigens in a series in an attempt to boost the most cross-reactive immunity (Fig

Patients with pernicious anemia have an irreversible cause of deficiency, so its important to ensure other factors do not contribute to further deficiency progression

Subjects were given vitamin B 12 supplements by intramuscular injection, as has been described in previous studies, which probably does not reflect levels one might achieve naturally
