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At the time, this was attributed to the fact that ketogenic diets induce a mild, transient bout of oxidative stress that could in turn activate the NRF2 pathway as a response (Milder et al., 2010)

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Consonance with these mechanistic pathways, the results of this review indicate favorable cardiac outcomes with L-carnitine supplementation, including reduced infarct size as well as lower incidence of heart failure, ventricular arrhythmia, total cardiac events, and all-cause mortality