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This process is mediated through the nucleotide-binding pocket within the subunit, where AMP competitively inhibits ATP binding and enhances kinase activity ( Through phosphorylation of downstream target proteins, AMPK establishes a multidimensional regulatory network that coordinates energy metabolism and cellular homeostasis

It has the ability to improve brain function because it can cross the protective membrane of the brain (blood-brain barrier), meaning that it can increase the energy metabolism of brain cells

Vestibular rehabilitation incorporates three types of exercise, which are individualized according to patients specific concerns 127 : Habituation