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The first two sessions of Prolotherapy were to his hips but did not improve his stiffness or his gait

[DOI] [PMC free article] [PubMed] [Google Scholar] 219.Liu Y, Harlow DE, Given KS, Owens GP, Macklin WB, Bennett JL

The hBD-3-mediated activation of fibroblasts involves the fibroblast growth factor receptor 1 (FGFR1)/Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) pathways, as evidenced by the inhibitory effects of pathway-specific inhibitors as illustrated in Figure 4

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