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In practice, many patients present with overlapping or mixed pain mechanisms, and the boundaries between nociceptive, neuropathic, and nociplastic pain are often blurred
Earlier studies have demonstrated activation of the NLRP3 inflammasome and increased expression of IL-1 in both type 1 (ref
Rao M, Nassiri V, Alhambra C, Snoeys J, Van Goethem F, Irrechukwu O, Aleo MD, Geys H, Mitra K, Will Y (2023) AI/ML models to predict the severity of drug-induced liver injury for small molecules
You cannot tell whether your homocysteine is elevated based on symptoms alone
