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This study aims to see the individual and combined effects of Angiotensin II type 2 (AT2) receptor agonist buloxibutid (also known as Compound 21 or C21) and sodium-glucose co-transporter-2 (SGLT-2) inhibitor empagliflozin (EMPA) on effects of hypertension (HT), which is common today, on the heart, and vascular tissue

Regarding all other medications, our review found no evidence to contravene their use in normal therapeutic doses to G6PD-deficient patients.There is a need for evidence-based global consensus regarding medication use in G6PD-deficient patients.

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