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In vivo studies have shown that excess lactate from astrocytic glycolysis disrupts synaptic plasticity and accelerates A aggregation, exacerbating cognitive impairment in APP/PS1 mice [114]

10.1038/ncomms11017 44

doi: 10.2967/jnumed.119.225680 51 CornfordEMYoungDPaxtonJWFinlayGJWilsonWRPardridgeWM
