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The spray voltage for both positive and negative modes was 3.5 kV and the capillary temperature was set to 320 C with a sheath gas rate of 35, aux gas of 10 and maximum spray current of 100 A
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However, excessive methionine intake shifts sulfur metabolism towards increased hydrogen sulfide (HS) production and sulfate excretion
By optimizing the LNP surface structure and ligands, the study achieved efficient siRNA delivery and substantial KRAS silencing
