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The top two abundant changed metabolic pathways were amino acid metabolism and lipid metabolism (Fig

This semi-essential amino acid supports comprehensive anti-aging mechanisms including reducing cellular senescence, protecting against cellular dysfunction, supporting mitochondrial health, and reducing inflammation

Our findings revealed that B12 deficient women had significant increase in expression of genes involved in the de novo FA synthesis (ACACA, FASN), elongation (ELOVL6, SCD), and TG biosynthesis pathways (GPAT2, LIPIN1) in both OmWAT and ScWAT compared to subjects with adequate B12 levels

Next we compared the effects of LC on normal tissue and cancer growth in vivo