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Fear often outpaces evidence in discussions about experimental compounds

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P., Dong, F

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While little is known about the role of GSTA4 in cancer, particularly in colorectal cancer, previous studies have demonstrated that transfection of primary cell lines with human GSTA4-expressing plasmids causes cellular transformation and immortalization via upregulation of transforming growth factor, cyclin-dependent kinase 2, and protein kinase C beta II and downregulation of p53 (35)

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Int J Mol Sci 21(20)

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