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Development of an inhalable, stimuli-responsive particulate system for delivery to deep lung tissue
Compared with Control cells, p53 KO cells exhibited far fewer nutlin-3induced changes in gene expression, consistent with most changes observed in Control cells being p53-dependent (Fig 3A)
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This represents an alternative strategy for metabolic applications where GH's fat-mobilizing properties are desired without the full GH/IGF-1 axis activation that GH secretagogues produce
