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Description
Glutamate is directly or indirectly involved in almost all brain functions, and the different glutamate transporters control glutamate levels in different ways

British Journal of Ophthalmology

However, research doesnt show that people without a deficiency or excess vitamin B12 would benefit from supplements

Although the reactions catalysed by Gdh2 and Gdh3 are reversible, the Gdh2-catalysed reaction favours the deamination of glutamateits catabolism to -ketoglutarate and ammonium 12
