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No increase in number of adverse events with increasing renal or hepatic impairment was observed, and no new safety or tolerability findings with cagrilintide were identified with renal or hepatic impairment
It balances measurement precision with practical injection volumes across the full titration range
We speculate that specificity of antigen presenting cells, such as macrophage, may need to be taken into consideration and probed further for development of an anti-tumor response
