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Description
The influxing cystine consists of two chains: The light chain solute carrier family 7 member 11 (SLC7A11) and the heavy chain solute carrier family 3 member 2 (SLC3A2, also termed CD98), which are bound together by disulfide bonds (19,35,36)
however, current research has revealed that the drugs anticancer effect is due to its effect on glutamine levels [90]
Reversal of cisplatin resistance by microRNA-139-5p-independent RNF2 downregulation and MAPK inhibition in ovarian cancer
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