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Cdk4/6 inhibition decreases tonic currents and mIPSC amplitude in the hippocampus The 4 subunit is a component of extra-synaptic, high-affinity GABA A Rs, which mediate tonic inhibition in the thalamus and hippocampus [23]

In addition, the degree of liver damage in acute hepatotoxicity can vary depending on factors, such as sex and species

the information below is extrapolated from authorised GLP-1 and GLP-1/GIP receptor agonists (such as semaglutide and tirzepatide) and should be interpreted accordingly