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This role is essential for maintaining plasma glucose availability, especially for glucose-dependent tissues

McConnell MJ, Moran JV, Abyzov A, Akbarian S, Bae T, Cortes-Ciriano I et al

Compared to the vehicle and GPE + GH groups, GPE effects in NSCs proliferation were shown by a significant increase in BrdU+ cells (representing labelled proliferating cells), while significant migration by GPEs in NSCs was presented by the wound closure rate, which was independent of cell proliferation

The cell cycle proteins S-phase kinase-associated protein-2 (Skp2) and Cyclin B1 are ubiquitinated and degraded by the E3 ligase APC/C