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Also, it can be recruited with the aim of improving physical and cognitive functions in athletes and the elderly
It may also prove useful for different types of opiate addiction
Neurology 75 , 9971002 (2010)
For instance, a high acetyl-CoA/CoA ratio in the mitochondrial matrix inhibits pyruvate dehydrogenase (PDH) that catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA (Pietrocola et al., 2015)
