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doi: 10.1007/s00018-024-05532-5

J Neurochem 157:684694
Many factors contribute to joint pain such as: Smoking Smoking cigarettes increases the risk of getting rheumatoid arthritis (RA)

Certain studies have suggested that tryptophan deprivation activates GCN2 kinase in CD4 + T cells [227] and that IDO-expressing DCs activate GCN2 kinase in CD8 + T cells [280]
