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Effect of different administration paradigms on cholinesterase inhibition following repeated chlorpyrifos exposure in late preweanling rats

Perez-Miralles, F
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Avoidance of First-Pass Metabolism : Medications delivered via the nasal route bypass the liver's first-pass metabolism, which is beneficial for drugs that are otherwise ineffective when taken orally due to metabolic transformation or degradation in the gastrointestinal tract
