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Researchers also concluded that glucocorticoid receptor signaling may cause muscle wasting in animals, suggesting that high glucocorticoid receptor signaling could be a risk factor for this condition [2]

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The Effects of Growth Hormone Receptor on Mitochondrial Biogenesis In recent decades, genetically engineered mouse strains ( GHR gene disrupted or knockout mouse) have become vital tools for exploring the various activities of GH and GHR in vivo (List et al., 2020)

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