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The CDC and clinical guidelines suggest that expecting 12 pounds weekly during the initial phase and 0.51 pound weekly during later phases represents a reasonable framework, though week-to-week fluctuations due to fluid retention, menstrual cycles, or dietary sodium intake are normal and should not cause alarm

That looks like a direct contradiction: one study says less pain, the other says more! What are we to make of this

Of those, 160,292 (43.5%) and 160,538 (43.6%) were deemed eligible for cohort 1 (incident users) and cohort 2 (prevalent users), respectively (see Supplementary Material, Table S4A and S4B)

[To me], this clearly points to the fact that people need to engage in a supportive primary care model to optimise all health outcomes. Dr Terri-Lynn South, Chair of RACGP Specific Interests Obesity Management, holds similar concerns