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Description
Ser is a substrate for mitochondrial onecarbon metabolism, which generates NADPH while converting Ser + tetrahydrofolate (THF) into glycine (Gly) + THF + formate through the activity of serine hydroxymethyl transferase 2 (SHMT2), methyleneTHF dehydrogenase (MTHFD) 2, and MTHFD1L
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Sora I, Takahashi N, Funada M, Ujike H, Revay RS, Donovan DM, et al
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