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Journal of Molecular Structure, Volumes 436437:153160

(2015) demonstrated that intraperitoneal administration of NAC improved motor coordination, reversed dopamine loss in the SN, and normalized the levels of essential mitochondrial proteinsdecreasing parkin and increasing dynamin-related protein 1 (Drp1)thus indicating a protective effect against mitochondrial fragmentation and disrupted turnover [94]

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Some considerations and risks of long-term use include metabolic effects that could be changes in insulin sensitivity and cardiovascular effects that could shift blood pressure or lipid levels in vulnerable individuals