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Description
Over Christmas I was very ill
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Dhamija (Bhopal, India) Objective: The overlap of two independent neurodegenerative diseases is a rare phenomenon and this case highlights the overlap of Parkinson's Disease (PD) and Amyotrophic Lateral Sclerosis (ALS)

Post-hoc subgroup findings are hypothesis-generating, not confirmatory they do not change the fact that the prospectively-defined primary endpoint failed

Critically, VD and VE also reinforce BBB integrity by up-regulating tight junction proteins (claudin-5, ZO-1) and suppressing MMP-9, disrupting the albumin-TGF-driven hyperexcitability cycle
