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38 Although progress has been made, some things are still to be determined

Modifiable risk factors in knee osteoarthritis: treatment implications. Rheumatology international 39.7 (2019): 1145-1157

In in vitro co-culture systems allowing direct contact, BM-MSCs remarkably suppressed the proliferation and -SMA expression of HSCs by activating the Notch signaling cascade and downregulating the PI3K/Akt pathway [179]

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