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At this point, the conclusion was clear
Because NO released from cavernous nerves represents the initiating event for erection, early disruption of nitrergic fibres renders subsequent vascular damage clinically more relevant and contributes to reduced efficacy of phosphodiesterase 5 inhibitors (PDE5-Is) in advanced stages of diabetic ED [17]
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If your degree of curvature is severe and/or you experience erectile dysfunction, a 3-piece penile prosthesis may be recommended as a treatment for Peyronies disease
