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Another study using ellagic acid to treat oxygen-glucose deprivation and reoxygenation models of rat cortical neurons cultured in vitro found a significantly reduced volume of cerebral infarction and improved neurological deficit score in rats by increasing the Bcl-2/Bax ratio (Rehman et al., 2019)
However, chronic antipsychotic exposure may account for some of the dendritic tree reduction and progressive cortical thinning repeatedly described in schizophrenia
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