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GLI-similar 1 (GLIS1) downregulation in CD8 + T cells slows cancer progression, increases infiltration, and enhances the anti-PD1 response in HCC
TCA cycle metabolites and cellular senescence Epigenetic modifications are increasingly being recognized as critical markers of cellular senescence, with posttranslational modifications of histones (such as methylation, acetylation, and succinylation) playing a significant role in this process
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