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Description
Dimethyl fumarate (DMF), an FDA-approved drug prescribed for the treatment of multiple sclerosis (55, 56), activates NRF2 by disrupting its interaction with KEAP1 ( Figure 7A ), allowing NRF2 to translocate to the nucleus and become transcriptionally active (5557)
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Notably, 91.9% of the combination group lost at least 5% of baseline weight, while 53.6% lost 20%
Tripeptide in human serum that prolongs survival of normal liver cells
