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Knackstedt, L

and Type V, although less common, is characterized by fat distribution predominantly in the calves Notably, some literature also describes involvement of the lower abdomen, especially in Types I and II, although this is not consistently reflected across all classification systems.8,15,21,22 Regarding morphological appearance, lipedema progresses through four clinical stages (Table 2): Stage I is characterized by smooth skin with thickened but soft subcutaneous tissue containing small nodules

van den Boogaard ML, Thijssen PE, Aytekin C, et al

J Anim Sci Biotechnol 7:20 Riond JL, Stiefel M, Wenk C, Wanner M (2003) Nutrition studies on protein and energy in domestic cats