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The formation of autophagosome membranes around ubiquitinated mitochondria is dependent on the binding of NDP52 and OPTN to the core autophagy proteins FIP200 and ATG9A, respectively [191, 192]

Alveolar macrophages (AMs) secrete exosomes that transport ficolin B (Fcn B), which in turn activates the cGAS-STING pathway, accelerating autophagy and iron death in lung epithelial cells [117]

10.1016/j.jpha.2015.11.005 7 BhaktaJ

GSTP1 methylation: A tissue biomarker that performs well in several types of malignancies The promoter region of the GSTP1 gene is usually affected by methylation, and changes in methylation status suppress normal gene expression, which may lead to weakening or loss of its detoxification and antioxidant functions