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revealed increased fat utilization, consistent with that obtained at ~23.5 mo

The resulting enhancement of connective tissue integrity makes it a key focus in musculoskeletal regeneration and aging-related bone metabolism research

Ultrapure water (18.2 M cm resistivity, Arium Comfort H2O-I-1-UV-T from Sartorius, Goettingen, Germany) or LC-MS grade water (LiChrosolv, Merck KGaA) was used throughout

