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Description
This approach is explored with small molecule drug erastin (named after eradicator of RAS and ST-expressing cells) identified to efficiently kill human tumor cells without affecting their isogenic normal cell counterparts [160]

10.1039/D4RA07646J 112 NidorfS

A key mechanism of SF involves the activation of the nuclear transcription factor Nrf2 (nuclear factor erythroid 2related factor 2), which orchestrates a suite of cytoprotective responses

Yet, functional imaging and peripheral biomarker measurements in patients with TRD are relatively scarce
