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Description
Despite the significant survival advantage it confers, ADT is associated with numerous adverse effects including increased risk for cardiovascular diseases, diabetes, sexual dysfunction, cognitive, and mood dysfunction, and sleep disturbance (Gonzalez et al., 2018

Dosage should start at 50 mg/kg/day, and be increased slowly to a maximum of 3 g/day (30 mL/day) while assessing tolerance and therapeutic response

Huang Q, et al

Pediatr Res 1995
