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Upon insulin stimulation, cells expressing normal IR showed robust activation of all the common downstream signalling pathways, including phosphorylation of IRS-1, Shc, Gab-1, Akt, ERK1/2 and p70S6K1-S6 pathway (Fig
Blood 104:133a, 2004
depletion of cellular GSH by selective inhibition of synthesis restores drug sensitivity to the resistant cells
Advances in ferroptosis-inducing agents by targeted delivery system in cancer therapy
