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In ME/CFS and Long COVID, researchers have identified a 'mitochondrial-peroxisomal vicious cycle.' As mitochondria attempt to generate adenosine triphosphate (ATP) for energy, damaged electron transport chains 'leak' electrons, creating highly reactive superoxide radicals
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doi: 10.1016/0014-5793(94)01230-X

USD 39.95 Prices may be subject to local taxes which are calculated during checkout Similar content being viewed by others Change history 13 July 2021 A Correction to this paper has been published: References Sies, H
Ehleben and colleagues applied biophysical methods like light absorption spectrophotometry of cytochromes, determination of NAD(P)H-dependent O 2 - formation and localization of OH by three-dimensional (3D) confocal laser scanning microscopy to reveal putative members of the oxygen sensing signal pathway leading to enhanced gene expression under hypoxia [4, 77]