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Superoxide dissociation can convert Fe 3+ into Fe 2+ through the Fenton-Habe-Wess cascading reaction catalyzed by iron

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Disturbances in the balance between pro- and anti-angiogenic factors can drive pathologic angiogenesis ( Physiologic Angiogenesis: Process and Types Blood vessels of the microvasculature are composed of two major cell types: endothelial cells and perivascular cells known as pericytes (Mazurek et al., 2017)