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Additionally, a high-salt diet promoted DSS-induced IBD progression by enhancing RIPK3 -dependent necroptosis in colonic epithelial cells [35]
Excess accumulation of these metals has been implicated in oxidative stress and the aggregation of misfolded proteins in conditions like AD and PD [188]

Turkler C, Onat T, Yildirim E, Kaplan S, Yazici GN, Mammadov R

Currently, studies on NCOA4 have revealed its potential dual role in either promoting (102) or inhibiting ferroptosis (103)
