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These analyses are then presented to the Ontario Health Technology Advisory Committee, whose mandate is to examine proposed health technologies in the context of available evidence and existing clinical practice, and to provide advice and recommendations to Ontario health care practitioners, the broader health care system, and the Ontario Ministry of Health and Long-Term Care

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Int J Mol Med, 2003

Lower concentrations around 0.05% are suitable for maintenance and sensitive skin, while higher concentrations closer to 0.5% may be more effective for treating deeper wrinkles or post-procedure recovery