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Since NAD + is present in only catalytic amounts in the cell and is an essential cofactor for glycolysis (and other reactions), there must be a mechanism for regeneration of NAD + if glycolysis is to continue
Mol Cell (2014) 54:13346

The first, mediated by NOX2, may negatively regulate T cell-dependent antibody production

Due to the limitations of MR, the lack of associations must be interpreted carefully
