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8B), which is partly due to accelerated proliferation and altered metabolism 25,26,27 , additional increases in intracellular ROS levels, which are tolerable for normal cells, become lethal to most cancer cells 15,27 (Fig
[DOI] [PMC free article] [PubMed] [Google Scholar] [57].Yuan J, Palioura S, Salazar JC, et al
Diamond J
In contrast, inhibiting ceramide synthesis in fat-fed streptozotocin (STZ)-treated rats has been shown to improve endothelial dysfunction by enhancing phosphorylation and NO release via the PI3K/Akt/eNOS pathway
