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Four participants did not complete the study: three due to complications from chronic medical conditions and one due to fatigue
This could be attributable to anabolic and catabolic new phenolic compounds or metabolites (Rashwan et al., 2021, 2022)
Serum creatinine is used as first test for the capacity of the kidney to filter substances from the blood (glomerular filtration) and is used before surgical procedures to assess the patients ability to clear the anesthetics
Further investigations are clearly warranted
