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Additionally, variants in folate transport genes such as SLC19A1 and the presence of folate receptor alpha autoantibodies have been associated with cerebral folate deficiency in children with ASD, further supporting a role for disrupted folate metabolism in neurodevelopmental vulnerability

This is simply not acceptable especially in cases where an infiltration or extravasation will lead to serious patient harm

Lewerenz J, Sato H, Albrecht P, Henke N, Noack R, Methner A et al

10.1089/neu.1990.7.13 J
