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Mujahid, A

In endothelial cells, a 24 h exposure to NAC resulted in the disruption of tight junctions due to a reduction in occludin, delocalization of claudin-5, and an increase in neuronal nitric oxide synthase (nNOS) expression, which led to increased permeability

Children's Hospital of Philadelphia

Lens opacification, or cataracts, are the leading cause of vision impairment and blindness worldwide ( Cortical cataract, the second most prevalent form of cataract, occurs earlier than age-related nuclear (ARN) cataract ( Figure 1A ) ( Figure 1B ) occurs when the intrinsic repair and protection mechanisms that exist to mitigate the effects of oxidative stress slowly deteriorate or become ineffective ( Figure 1C ) are characterised by dysplasia of the equatorial epithelial cells ( Figure 1 (B) Nuclear cataract, from Ophthalmic Atlas Images by EyeRounds.org