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Description
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Most protocols dose by injection close to the site of injury (subcutaneous), though no human pharmacokinetic standard exists
URAT1 is found on the basolateral membrane of these epithelial cells 42 , which suggests these two proteins are functioning in concert as transcellular UA transporters, as they do to achieve resorption in the kidney
Subgroup analysis and meta-regression were performed to find the source of heterogeneity
