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In POTS, the autonomic nervous system struggles to regulate heart rate and blood vessel constriction, often resulting in blood pooling in the lower extremities and a racing heart upon standing
In type B intercalated cells the V-ATPase is localized to the basolateral membrane and effluxes H + to the blood
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[DOI] [PMC free article] [PubMed] [Google Scholar] 113.Lu SC
