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Description
Infiltration/extravasation

That often shows up as fatigue, slower recovery, and a skin that looks less refreshed [10]

Watari I, Oka S, Tanaka S, Aoyama T, Imagawa H, Shishido T,
They have four key domains: a scaffold domain, or trimerization domain (comprised of transmembrane domains 1, 2, 4, 5), which remains stationary
